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11 Work-From-Home Jobs That Pay Over $100K (Yes, Really)

You can earn over $100,000 annually and work from home at the same time.

By Adam Palasciano

Edited by Jessica Gibson

Updated Nov. 26, 2025

Remote work has become increasingly popular, offering flexibility and the opportunity to earn a substantial income from the comfort of your home.

If you're looking for high-paying work-from-home opportunities and want to start building more wealth, here are 12 jobs that can pay over $100,000 annually.

Editor's note: Salary data taken from the Bureau of Labor Statistics.

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Regional Sales Director

Average annual salary: $138,060

Regional sales directors manage sales teams within a specific region, develop sales strategies, and ensure targets are met.

Proven sales experience and strong leadership skills are essential. Experience in sales strategy development and team management is also crucial.

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Senior Product Manager

Average annual salary: $121,440

Senior product managers oversee product development from concept to production, working with business and technical teams to meet customer needs and market demands.

Extensive experience in business and commerce is important, though an M.B.A. is not necessary. Familiarity with technical processes and experience in product development and marketing are beneficial.

Data Scientist

Average annual salary: $112,590

Data scientists analyze large datasets using computing frameworks to develop actionable insights across various industries. Advanced degrees in engineering, statistics, math, or computer science are needed.

Beyond technical skills, strong communication abilities are crucial for translating data into understandable insights. Demonstrating a history of effective data storytelling can give you a competitive edge.

Senior Software Engineer

Average annual salary: $131,450

Senior software engineers design, develop, and maintain software systems, collaborating with other developers and stakeholders to create scalable and efficient solutions.

A B.A. or B.S. in computer science or a related field is typically required, along with extensive experience in programming languages such as Java, C++, and Python. Strong problem-solving skills and the ability to work collaboratively are essential.

Psychiatrist

Average annual salary: $239,200

Psychiatrists meet with patients via video calls, conduct evaluations and diagnostics, develop treatment plans, and guide staff on medical protocols.

In addition to proper accreditation and a state license to practice, proficiency with teleconferencing software like Zoom or Skype is essential. Highlighting strong documentation and communication skills is crucial, as they are key to the job.

Engineering Manager

Average annual salary: $167,740

Engineering managers oversee engineering projects, manage teams, and ensure that engineering solutions meet technical specifications and business goals.

A degree in engineering, combined with management experience and strong leadership skills, is essential. Demonstrating a successful track record in managing engineering projects can be advantageous.

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Senior Information Security Consultant

Average annual salary: $124,910

This role focuses on a business's remediation strategies and network security, including risk assessments, IT audits, and penetration testing to ensure compliance and security.

Certifications such as CISSP, CEH, CISA, and CISM can be beneficial. Experience in IT security, compliance, and adherence to National Institute of Standards and Technology guidelines is crucial.

Medical Director

Average annual salary: $1117,960

Medical directors lead medical departments or health care organizations, overseeing hiring and supervising staff and executing and developing medical care strategies. It's important to note that some travel and on-site presence may be required.

Experience in patient care and administrative supervision is essential. Strong communication and writing skills are necessary, as the medical director often represents the department or organization publicly.

Software Engineer

Average annual salary: $131,450

Software engineers develop, maintain, and improve software applications using programming languages such as Java, Javascript, SQL, C++, and Python.

A degree in computer science or a related field, such as mathematics, software engineering, or information systems, along with proficiency in multiple programming languages and collaborative working skills, is essential.

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Senior Business Analyst

Average annual salary: $101,190

Senior business analysts collect and analyze data to better understand business challenges and needs, working with managers to implement best practices and solutions.

Excellent time management and problem-solving skills are essential. Experience in IT, management, and human resources, along with excellent communication abilities, is crucial.

Actuarial Analyst

Average annual salary: $125,770

Actuarial analysts use statistical models to assess risk and costs in industries such as insurance, predicting financial needs for future events.

Professional certification and proficiency in Excel are necessary. You'll also need to pass several exams, like Exam FM and Exam P. Experience in data analysis, risk management, or investments can be advantageous.

Bottom line

Finding a high-paying remote job can be a game-changer for your career and lifestyle. With the right skills and qualifications, these roles offer lucrative opportunities to make money from home.

Are you ready to explore these options and transform your professional life? Consider what steps you need to take to qualify for these positions and start your journey toward a rewarding remote career today.

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